BOLA flow filters suitable for overpressure or vacuum, usable for example as added filter or as large-area in-line apparatus in a line system. Suitable for temperatures up to +160°C. The optionally available filtering membranes can be exchanged easily. Tubing can be connected to GL threads by means of the included laboratory screw joints. The filters are produced without plasticisers and have an almost universal chemical resistance. They do not release any trace elements into the filtrate. Due to the non-adhesive surface, they are easy to clean and can be reused.